Phosphatase and tensin homologue growth suppression without phosphatase
نویسندگان
چکیده
منابع مشابه
Phosphatase and tensin homologue growth suppression without phosphatase.
L ike an actor in a memorable role, proteins too are typecast by their first prominent function in the cell. Such has been the case with the potent tumor suppressor phosphatase and tensin homologue (PTEN) in its widely acclaimed role as a phosphatase. PTEN removes phosphates from specific lipids and from tyrosines on particular proteins, leading to inhibition of growth-promoting signals. Mutati...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2005
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0500089102